Resources
应用简讯
应用手册
- Quantitative Microscopy of Angiogenesis in Zebrafish Embryos (December 6, 2018)
- Stimulation of IL-2 Secretion in Human Lymphocytes (March 21, 2018)
- Using Acridine Orange to Measure Cell Death in Ethanol Treated Zebrafish Embryos (December 27, 2017)
- Rapid Measurement of IgG Using Fluorescence Polarization (September 15, 2017)
- Mitochondrial Membrane Potential by Object Spot Counting (September 11, 2017)
- Automated Label-Free Cell Migration Assays using Magnetic 3D Bioprinting (August 16, 2017)
- An Automated Walk-Away System to Perform Differentiation of 3D Mesenchymal Stem Cell Spheroids (December 16, 2016)
- Monitoring Viral Infection of Mammalian Cells using Digital Fluorescence Microscopy (July 5, 2016)
- Analysis of Cell Retention Following Rigorous Automated Cell Fixation and Staining (December 18, 2015)
- Imaging and Analysis of a High Density Cell Migration Assay (November 25, 2014)
- Applied Robotics for Enhanced Throughput Options in Microscopy As Demonstrated by Automated Tissue Microarray (TMA) Imaging (November 6, 2014)
- Investigation of Cell Migration using a High Density Cell Exclusion Assay and Automated Microplate Imager (July 10, 2013)
引用文献
软件&自动化
Gen5软件用于用于显微成像的特性 (67)
- Pandanaboina, SC;Alghazali, KM;Nima, ZA;Alawajji, RA;Sharma, KD;Watanabe, F;Saini, V;Biris, AS;Srivatsan, M; (2019) "Plasmonic Nano surface for neuronal differentiation and manipulation." Nanomedicine
- Fachi, JL;Felipe, JS;Pral, LP;da Silva, BK;Corrêa, RO;de Andrade, MCP;da Fonseca, DM;Basso, PJ;Câmara, NOS;de Sales E Souza, ÉL;Dos Santos Martins, F;Guima, SES;Thomas, AM;Setubal, JC;Magalhães, YT;Forti, FL;Candreva, T;Rodrigues, HG;de Jesus, MB;Consonni, SR;Farias, ADS;Varga-Weisz, P;Vinolo, MAR; (2019) "Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism." Cell Rep
- Santolla, MF;Vivacqua, A;Lappano, R;Rigiracciolo, DC;Cirillo, F;Galli, GR;Talia, M;Brunetti, G;Miglietta, AM;Belfiore, A;Maggiolini, M; (2019) "GPER Mediates a Feedforward FGF2/FGFR1 Paracrine Activation Coupling CAFs to Cancer Cells toward Breast Tumor Progression." Cells
- Lu, W;Chen, S;Yu, J;Behrens, R;Wiggins, J;Sherer, N;Liu, SL;Xiong, Y;Xiang, SH;Wu, L; (2019) "The Polar Region of the HIV-1 Envelope Protein Determines Viral Fusion and Infectivity by Stabilizing the gp120-gp41 Association." J. Virol.
- Spratt, DE;Barber, KR;Marlatt, NM;Ngo, V;Macklin, JA;Xiao, Y;Konermann, L;Duennwald, ML;Shaw, GS; (2019) "A subset of calcium-binding S100 proteins show preferential heterodimerization." FEBS J.
- O'Farrell, H;Harbourne, B;Kurlawala, Z;Inoue, Y;Nagelberg, AL;Martinez, VD;Lu, D;Oh, MH;Coe, BP;Thu, KL;Somwar, R;Lam, S;Lam, WL;Unni, AM;Beverly, L;Lockwood, WW; (2019) "Integrative Genomic Analyses Identifies GGA2 as a Cooperative Driver of EGFR-Mediated Lung Tumorigenesis." J Thorac Oncol
- Madak-Erdogan, Z;Band, S;Zhao, YC;Smith, BP;Kulkoyluoglu-Cotul, E;Zuo, Q;Santaliz Casiano, A;Wrobel, K;Rossi, G;Smith, RL;Kim, SH;Katzenellenbogen, JA;Johnson, ML;Patel, M;Marino, N;Storniolo, AMV;Flaws, JA; (2019) "Free fatty acids rewire cancer metabolism in obesity-associated breast cancer via estrogen receptor and mTOR signaling." Cancer Res.
- López-Porras, A;Elizondo, C;Chaves, A;Camus, A;Griffin, M;Kenelty, K;Barum, S;Barquero-Calvo, E;Soto, E; (2018) "Application of multiplex quantitative Polymerase chain reaction methods to detect common bacterial fish pathogens in Nile tilapia, Oreochromis niloticus, hatcheries in Costa Rica." J World Aquacult Soc
- de la Vega, L;Rosas Gomez, DA;Abelseth, E; (2018) "3D Bioprinting Human Induced Pluripotent Stem Cell-Derived Neural Tissues Using a Novel Lab-on-a-Printer Technology." Applied Sciences
- Meng, P;Chen, ZG;Zhang, TT;Liang, ZZ;Zou, XL;Yang, HL;Li, HT; (2018) "IL-37 alleviates house dust mite-induced chronic allergic asthma by targeting TSLP through the NF-κB & ERK1/2 signaling pathways." Immunol. Cell Biol.
- Parikh, P;Britt, RD;Manlove, LJ;Wicher, SA;Roesler, A;Ravix, J;Teske, J;Thompson, MA;Sieck, GC;Kirkland, JL;LeBrasseur, N;Tschumperlin, DJ;Pabelick, CM;Prakash, YS; (2018) "Hyperoxia-Induced Cellular Senescence in Fetal Airway Smooth Muscle Cells." Am. J. Respir. Cell Mol. Biol.
- Hivechi, A;Hajir Bahrami, S;Siegel, RA; (2018) "Investigation of morphological, mechanical and biological properties of cellulose nanocrystal reinforced electrospun gelatin nanofibers." Int. J. Biol. Macromol.
- Lee, YM;Kim, MK;Choo, H;Chong, Y; (2018) "Conjugation with Phenylalanine Enhances Autophagy-Inducing Activity of (-)-Epigallocatechin Gallate in Hepatic Cells." J. Agric. Food Chem.
- Pohl-Guimarães, F;Yang, C;Dyson, KA;Wildes, TJ;Drake, J;Huang, J;Flores, C;Sayour, EJ;Mitchell, DA; (2018) "RNA-Modified T Cells Mediate Effective Delivery of Immunomodulatory Cytokines to Brain Tumors." Mol. Ther.
- Unni, AM;Harbourne, B;Oh, MH;Wild, S;Ferrarone, JR;Lockwood, WW;Varmus, H; (2018) "Hyperactivation of ERK by multiple mechanisms is toxic to RTK-RAS mutation-driven lung adenocarcinoma cells." Elife
- Halvorsen, E;Franks, S;Wadsworth, B;Harbourne, B;Cederberg, R;Steer, C;Martinez-Gonzalez, I;Calder, J;Lockwood, W;Bennewith, K; (2018) "IL-33 increases ST2+ Tregs and promotes metastatic tumour growth in the lungs in an amphiregulin-dependent manner." OncoImmunology
- Wilkinson, A;Diep, J;Dai, S;Liu, S;Ooi, Y;Song, D;Li, T;Horton, J;Zhang, X;Liu, C;Trivedi, D;Ruppel, K;Vilches-Moure, J;Casey, K;Mak, J;Cowan, T;Elias, J;Nagamine, C;Spudich, J;Cheng, X;Carette, J;Gozani, O; (2018) "SETD3 is an actin histidine methyltransferase that prevents primary dystocia." Nature
- Pereira, AM;Pinto, E;Matos, E;Castanheira, F;Almeida, AA;Baptista, CS;Segundo, MA;Fonseca, AJM;Cabrita, ARJ; (2018) "Mineral Composition of Dry Dog Foods: Impact on Nutrition and Potential Toxicity." J. Agric. Food Chem.
- Cabral, GRA;Wang, ZT;Sibley, LD;DaMatta, RA (2018) "Inhibition of Nitric Oxide Production in Activated Macrophages Caused by Toxoplasma gondii Infection Occurs by Distinct Mechanisms in Different Mouse Macrophage Cell Lines." Front Microbiol
- Miller, MH;Shehat, MG;Alcedo, KP;Spinel, LP;Soulakova, J;Tigno-Aranjuez, JT (2018) "Frontline Science: RIP2 promotes house dust mite-induced allergic airway inflammation." J. Leukoc. Biol.
- Russo, C;Brickelbank, N;Duckett, C;Mellor, S;Rumbelow, S;Clench, MR (2018) "Quantitative Investigation of Terbinafine Hydrochloride Absorption into a Living Skin Equivalent Model by MALDI-MSI." Anal. Chem.
- Godwin, TD;Kelly, ST;Brew, TP;Bougen-Zhukov, NM;Single, AB;Chen, A;Stylianou, CE;Harris, LD;Currie, SK;Telford, BJ;Beetham, HG;Evans, GB;Black, MA;Guilford, PJ; (2018) "E-cadherin-deficient cells have synthetic lethal vulnerabilities in plasma membrane organisation, dynamics and function." Gastric Cancer
- Buglak, NE;Jiang, W;Bahnson, ESM (2018) "Cinnamic aldehyde inhibits vascular smooth muscle cell proliferation and neointimal hyperplasia in Zucker Diabetic Fatty rats." Redox Biol
- Smith, KM;Tsimbalyuk, S;Edwards, MR;Cross, EM;Batra, J;Soares da Costa, TP;Aragão, D;Basler, CF;Forwood, JK (2018) "Structural basis for importin alpha 3 specificity of W proteins in Hendra and Nipah viruses." Nat Commun
- Park, YJ;Kenney, GE;Schachner, LF;Kelleher, NL;Rosenzweig, AC; (2018) "Repurposed HisC Aminotransferases Complete the Biosynthesis of Some Methanobactins." Biochemistry
- Overholt, MF;Dilger, AC;Boler, DD;Kerr, BJ; (2018) "Influence of feeding thermally peroxidized soybean oil on growth performance, digestibility, and gut integrity in finishing pigs." J. Anim. Sci.
- Hurem, S; (2018) "Two-generational study of biological effects from gamma radiation exposure during sensitive life stages in the zebrafish." Thesis
- Dang, A;Larson, B; (2018) "Brightfield and Fluorescence Imaging using 3D PrimeSurface® Ultra-Low Attachment Microplates." J Immunol
- Kai, K;Iwamoto, T;Zhang, D;Shen, L;Takahashi, Y;Rao, A;Thompson, A;Sen, S;Ueno, NT; (2018) "CSF-1/CSF-1R axis is associated with epithelial/mesenchymal hybrid phenotype in epithelial-like inflammatory breast cancer." Sci Rep
- Angela K. Berger, Hong Yi, Daniel B. Kearns, Bernardo A. Mainou (2017) "Bacteria and bacterial envelope components enhance mammalian reovirus thermostability." PLoS Pathog
- Kang, D;Lee, S;Ryu, KS;Cheong, HK;Kim, EH;Park, CJ; (2018) "Interaction of replication protein A with two acidic peptides from human Bloom syndrome protein." FEBS Lett.
- Trejo-Moreno, C;Méndez-Martínez, M;Zamilpa, A;Jiménez-Ferrer, E;Perez-Garcia, MD;Medina-Campos, ON;Pedraza-Chaverri, J;Santana, MA;Esquivel-Guadarrama, FR;Castillo, A;Cervantes-Torres, J;Fragoso, G;Rosas-Salgado, G; (2018) "Cucumis sativus Aqueous Fraction Inhibits Angiotensin II-Induced Inflammation and Oxidative Stress In Vitro." Nutrients
- Lindblom, SC;Gabler, NK;Dilger, RN;Olson, ZF;Loving, CL;Kerr, BJ; (2018) "Influence of feeding thermally peroxidized soybean oil on oxidative status in growing pigs." J. Anim. Sci.
- Leistra, AN;Mihailovic, MK;Contreras, LM; (2018) "Fluorescence-Based Methods for Characterizing RNA Interactions In Vivo." Methods Mol. Biol.
- Murthy, D;Vernucci, E;Goode, G;Abrego, J;Singh, PK; (2018) "Evaluating the Metabolic Impact of Hypoxia on Pancreatic Cancer Cells." Methods Mol. Biol.
- Unni, AM;Harbourne, B;Oh, MH;Wild, S;Lockwood, WW;Varmus, H; (2017) "Hyperactivation of extracellular signal-regulated kinase (ERK) by RAS-mediated signaling or inhibition of dual specificity phosphatase 6 (DUSP6) is associated with toxicity in lung adenocarcinoma cells with mutations in KRAS or EGFR." bioRxiv
- Wright, RM; (2017) "Intraspecific variation in corals' responses to environmental stressors." Thesis
- Sánchez-Valdéz, FJ;Padilla, A;Wang, W;Orr, D;Tarleton, RL; (2017) "Spontaneous dormancy protects Trypanosoma cruzi during extended drug exposure." bioRxiv
- Borah, N;Gunawardana, S;Torres, H;McDonnell, S;Van Slambrouck, S; (2017) "5, ,6,7,3',4',5'-Hexamethoxyflavone inhibits growth of triple-negative breast cancer cells via suppression of MAPK and Akt signaling pathways and arresting cell cycle." International Journal of Oncology
- Bell, JB;Eckerdt, F;Dhruv, H;Finlay, D;Peng, S;Kim, S;Kroczynska, B;Beauchamp, E;Alley, K;Clymer, J;Goldman, S;Cheng, SY;James, CD;Nakano, I;Horbinski, C;Mazar, AP;Vuori, K;Kumthekar, P;Raizer, J;Berens, ME;Platanias, LC; (2017) "Differential Response of Glioma Stem Cells to Arsenic Trioxide Therapy is Regulated by MNK1 and mRNA Translation." Mol. Cancer Res.
- Slominski, AT;Kim, TK;Hobrath, JV;Janjetovic, Z;Oak, ASW;Postlethwaite, A;Lin, Z;Li, W;Takeda, Y;Jetten, AM;Tuckey, RC; (2017) "Characterization of a new pathway that activates lumisterol in vivo to biologically active hydroxylumisterols." Sci Rep
- Mehrpouya-Bahrami, P;Chitrala, KN;Ganewatta, MS;Tang, C;Murphy, EA;Enos, RT;Velazquez, KT;McCellan, J;Nagarkatti, M;Nagarkatti, P; (2017) "Blockade of CB1 cannabinoid receptor alters gut microbiota and attenuates inflammation and diet-induced obesity." Sci Rep
- Hurem, S;Gomes, T;Brede, DA;Lindbo Hansen, E;Mutoloki, S;Fernandez, C;Mothersill, C;Salbu, B;Kassaye, YA;Olsen, AK;Oughton, D;Aleström, P;Lyche, JL; (2017) "Parental gamma irradiation induces reprotoxic effects accompanied by genomic instability in zebrafish (Danio rerio) embryos." Environ. Res.
- Hayashi, T;Jean, M;Huang, H;Simpson, S;Santoso, NG;Zhu, J; (2017) "Screening of an FDA-approved compound library identifies levosimendan as a novel anti-HIV-1 agent that inhibits viral transcription." Antiviral Res.
- Prasad, A;Astete, CE;Bodoki, AE;Windham, M;Bodoki, E;Sabliov, CM; (2017) "Zein Nanoparticles Uptake and Translocation in Hydroponically Grown Sugar Cane Plants." J. Agric. Food Chem.
- author, JA;Koch, LG;author, SL;author, SC;Zhu, W;Ma, X;author, AG;author, LD;author, RF;author, JG;Hock, C;Nitsch, RM;author, JB;author, AJ;author, FM;Samayoa, J;Turan, T;author, DA;author, AN;Huhtala, T;Shatillo, A;Puoliväli, J;Heikkinen, T;Bragge, T;Lehtimäki, K;author, AJ;author, KS;author, DL;Miedel, M;Jia, S;Soto-Guterriez, A;Stern, A;Gough, A; (2017) "Inaugural Charles River World Congress on Animal Models in Drug Discovery and Development." Journal of Translational Medicine
- Tõnis Laasfeld, Sergei Kopanchuk, and Ago Rinken (2017-10) "Image-based cell-size estimation for baculovirus quantification." BioTechniques
- Becerril-Chávez, H;Colín-González, AL;Villeda-Hernández, J;Galván-Arzate, S;Chavarría, A;de Lima, ME;Túnez, I;Santamaría, A; (2017) "Protective effects of S-allyl cysteine on behavioral, morphological and biochemical alterations in rats subjected to chronic restraint stress: Antioxidant and anxiolytic effects." Journal of Functional Foods
- Saugstad, JA;Lusardi, TA;Van Keuren-Jensen, KR;Phillips, JI;Lind, B;Harrington, CA;McFarland, TJ;Courtright, AL;Reiman, RA;Yeri, AS;Kalani, MY;Adelson, PD;Arango, J;Nolan, JP;Duggan, E;Messer, K;Akers, JC;Galasko, DR;Quinn, JF;Carter, BS;Hochberg, FH; (2017) "Analysis of extracellular RNA in cerebrospinal fluid." Journal of Extracellular Vesicles
- Brown, KM;Long, S;Sibley, LD; (2017) "Plasma Membrane Association by N-Acylation Governs PKG Function in Toxoplasma gondii." MBio
- Schaaf, K;Smith, SR;Hayley, V;Kutsch, O;Sun, J; (2017) "A High-throughput Compatible Assay to Evaluate Drug Efficacy against Macrophage Passaged Mycobacterium tuberculosis." J Vis Exp
- Khan, SY;Awad, EM;Oszwald, A;Mayr, M;Yin, X;Waltenberger, B;Stuppner, H;Lipovac, M;Uhrin, P;Breuss, JM; (2017-03-01) "Premature senescence of endothelial cells upon chronic exposure to TNFα can be prevented by N-acetyl cysteine and plumericin." Sci Rep
- Yousefi, F;Ataei, F;Mortazavi, M;Hosseinkhani, S; (2017-03-18) "Bifunctional role of leucine 300 of firefly luciferase in structural rigidity." Int. J. Biol. Macromol
- Li, L;LaBarbera, D; (2016) "3D High-Content Screening of Organoids for Drug Discovery." Comprehensive Medicinal Chemistry, 3rd Edition
- Wang, Y;Gable, T;Ma, MZ;Clark, D;Zhao, J;Zhang, Y;Liu, W;Mao, L;Mei, Y; (2017-03-17) "A piRNA-like Small RNA Induces Chemoresistance to Cisplatin-Based Therapy by Inhibiting Apoptosis in Lung Squamous Cell Carcinoma." Mol Ther Nucleic Acids
- Torgersen, LN (2016) "Levels of emerging and traditional organic Pollutants in Northern Goshawk (Accipiter gentilis) from Trøndelag. Potential Effects on oxidative Stress." Thesis
- Morten, BC;Scott, RJ;Avery-Kiejda, KA; (2016) "Comparison of Three Different Methods for Determining Cell Proliferation in Breast Cancer Cell Lines." J Vis Exp
- Bell, JB;Eckerdt, F;Alley, K;Magnusson, LP;Hussain, H;Bi, Y;Arslan, AD;Clymer, J;Alvarez, AA;Goldman, S;Cheng, SY;Nakano, I;Horbinski, C;Davuluri, RV;James, CD;Platanias, LC; (2016) "MNK Inhibition Disrupts Mesenchymal Glioma Stem Cells and Prolongs Survival in a Mouse Model of Glioblastoma." Mol. Cancer Res.
- Rochford, K;Chen, F;Waguespack, Y;Figliozzi, RW;Kharel, MK;Zhang, Q;Martin-Caraballo, M;Hsia, SV; (2016) "Volatile Organic Compound Gamma-Butyrolactone Released upon Herpes Simplex Virus Type -1 Acute Infection Modulated Membrane Potential and Repressed Viral Infection in Human Neuron-Like Cells." PLoS ONE
- Dalecki, AG;Wolschendorf, F; (2016) "Development of a web-based tool for automated processing and cataloging of a unique combinatorial drug screen." J. Microbiol. Methods
- Beane, OS;Darling, LE;Fonseca, VC;Darling, EM; (2016) "Disparate Response to Methotrexate in Stem Versus Non-Stem Cells." Stem Cell Rev
- Dalecki, AG;Crawford, CL;Wolschendorf, F; (2016) "Targeting Biofilm Associated Staphylococcus aureus Using Resazurin Based Drug-susceptibility Assay." J Vis Exp
- Brad Larson, Leonie Rieger, Hubert Tseng, Glauco R. Souza, Aleksandra Velkova-Krei (2016-06-23) "3D-Migrationsassays im Hochdurchsatz." BIOSpektrum
- Speer, SD;Li, Z;Buta, S;Payelle-Brogard, B;Qian, L;Vigant, F;Rubino, E;Gardner, TJ;Wedeking, T;Hermann, M;Duehr, J;Sanal, O;Tezcan, I;Mansouri, N;Tabarsi, P;Mansouri, D;Francois-Newton, V;Daussy, CF;Rodriguez, MR;Lenschow, DJ;Freiberg, AN;Tortorella, D;Piehler, J;Lee, B;García-Sastre, A;Pellegrini, S;Bogunovic, D; (2016) "ISG15 deficiency and increased viral resistance in humans but not mice." Nat Commun
- Hevia, MA;Canessa, P;Müller-Esparza, H;Larrondo, LF; (2015) "A circadian oscillator in the fungus Botrytis cinerea regulates virulence when infecting Arabidopsis thaliana." Proc. Natl. Acad. Sci. U.S.A.
- Shashikant Srivastava, Jotam G. Pasipanodya, Geetha Ramachandran, Devyani Deshpande, Stephen Shuford, Howland E. Crosswell, Kayle N. Cirrincione, Carleton M. Sherman, Soumya Swaminathan, Tawanda Gumbo (2016-02-27) "A Long-term Co-perfused Disseminated Tuberculosis-3D Liver Hollow Fiber Model for Both Drug Efficacy and Hepatotoxicity in Babies." EBioMedicine
- Tatiane Oliveira, Camila A. Figueiredo, Carlos Brito, Alexander Stavroullakis, Ana Carolina Ferreira, Getulio Nogueira-Filho and Anuradha Prakki (2015) "Allium cepa L. and Quercetin Inhibit RANKL/Porphyromonas gingivalis LPS-Induced Osteoclastogenesis by Downregulating NF-κB Signaling Pathway." Evidence-Based Complementary and Alternative Medicine
科学海报
技术注释
- Agilent Seahorse XF Imaging & Cell Counting Software (June 28, 2018)
- Automated Cell Counting with High Contrast Brightfield and EVE Counting Slides (November 29, 2017)
- Measuring Confluence Using High Contrast Brightfield (September 5, 2017)
- High Contrast Brightfield (October 27, 2016)
- BioTek Counting Chamber (Hemocytometer) and Adapter - Instructions for Use (June 11, 2015)
动态摘要
网络视频
- Image Analysis 101 - Case Studies in Microbiology - On Demand (November 7, 2018)
- Quantitative Intracellular and Intranuclear Spot Analysis Using Digital Microscopy (November 29, 2017)
- Enabling Quantitative Cellular Imaging (November 29, 2016)
- Phenotypic and MoA Analysis of Anti-Metastatic Molecules using 3D Spheroid-Based Tumor Invasion Assays, Kinetic Microplate Detection, and Cellular Microscopy (May 11, 2015)