Resources
应用手册
- Automated Scoring of Acid-fast Bacteria (AFB) by Fluorescent Smear Microscopy (October 16, 2019)
- Nuclear Translocation of RelA in Stimulated Macrophages (September 18, 2019)
- Automated Analysis of Neutrophil NETosis Activity (April 30, 2019)
- Image Analysis of Herpesvirales Specificity Challenge using Direct Fluorescence Antibody Assay (DFA) (March 29, 2019)
- Analyzing Wound Healing in Zebrafish Embryos (February 11, 2019)
- Automated Image Screening of Zebrafish Embryos Exposed to Developmental Toxins (January 4, 2019)
- Quantitative Microscopy of Angiogenesis in Zebrafish Embryos (December 6, 2018)
- Determination of Cell Cycle Time (December 6, 2018)
- Advanced Wound Healing Assay Workflow using Automated Scratch Wound Creation, High Contrast Brightfield and Fluorescence Kinetic Imaging (December 6, 2018)
- Thapsigargin-induced Cellular Stress Response and Inhibition of Gq-dependent Calcium Signaling (October 5, 2018)
- Characterizing Gs- and Gi-dependent Regulation of cAMP Levels in Real Time with cADDis Biosensor and Automated Live Cell Imaging (March 29, 2018)
- Stimulation of IL-2 Secretion in Human Lymphocytes (March 21, 2018)
- Using Acridine Orange to Measure Cell Death in Ethanol Treated Zebrafish Embryos (December 27, 2017)
- Brightfield and Fluorescence Imaging using 3D PrimeSurface® Ultra-Low Attachment Microplates (December 21, 2017)
- Automated Imaging Assay for Characterizing Ca2+ Flux with R-GECO Biosensor (September 28, 2017)
- Mitochondrial Membrane Potential by Object Spot Counting (September 11, 2017)
- Lipid Accumulation in HepG2 Cells Exposed to Free Fatty Acids (August 14, 2017)
- Comparison of Different Cell Types for Neutral Lipid Accumulation (August 14, 2017)
- Automation of Non-Alcoholic Fatty Liver Disease Model Assay (August 14, 2017)
- Autophagy Analysis Using Object Spot Counting (July 11, 2017)
- Characterizing Calcium Mobilization using Kinetic Live Cell Imaging (January 26, 2017)
- Monitoring Saccharomyces cerevisiea Growth with Brightfield Microscopy in Real Time (July 20, 2016)
- Performance of a Label-Free Image-Based 2D Scratch Wound Healing Assay to monitor Cell Migration and its Inhibition (June 29, 2016)
- Oridonin Perfusion Causes Cytotoxicity in U-2 OS Cells (June 29, 2016)
引用文献
细胞成像&显微镜
Lionheart FX Automated Microscope (37)
- Ornell, K;Mistretta, K;Newman, E;Ralston, C;Coburn, J; (2019) "Three-Dimensional, Scaffolded Tumor Model to Study Cell-Driven Microenvironment Effects and Therapeutic Responses." ACS Biomater. Sci. Eng.
- Zheng, P;Hu, M;Xie, Y;Yu, Y;Jaaro-Peled, H;Huang, XF; (2019) "Aripiprazole and haloperidol protect neurite lesions via reducing excessive D2R-DISC1 complex formation." Prog. Neuropsychopharmacol. Biol. Psychiatry
- Ling, T;Maier, J;Das, S;Budhraja, A;Bassett, R;Potts, MB;Shelat, A;Rankovic, Z;Opferman, JT;Rivas, F; (2019) "Identification of substituted 5-membered heterocyclic compounds as potential anti-leukemic agents." Eur J Med Chem
- Seo, Y;Lee, J;Park, S;Namkung, W;Kim, I; (2020) "Expansion of chemical space based on a pyrrolo[1,2-a]pyrazine core: Synthesis and its anticancer activity in prostate cancer and breast cancer cells." European Journal of Medicinal Chemistry
- Almeida, LC;Bauermeister, A;Rezende-Teixeira, P;Santos, EAD;Moraes, LAB;Machado-Neto, JA;Costa-Lotufo, LV; (2019) "Pradimicin-IRD exhibits antineoplastic effects by inducing DNA damage in colon cancer cells." Biochem. Pharmacol.
- Xie, DM;Li, YL;Li, J;Li, Q;Lu, G;Zhai, Y;Zhang, J;Huang, Z;Gao, X; (2019) "CD51 distinguishes a subpopulation of bone marrow mesenchymal stem cells with distinct migratory potential: a novel cell-based strategy to treat acute myocardial infarction in mice." Stem Cell Res Ther
- Wang, P;Hua, X;Bryner, YH;Liu, S;Gitter, CB;Dai, J; (2019) "Haspin inhibition delays cell cycle progression through interphase in cancer cells." J. Cell. Physiol.
- Tang, X;Fu, X;Liu, Y;Yu, D;Cai, SJ;Yang, C; (2019) "Blockade of Glutathione Metabolism in IDH1-Mutated Glioma." Mol. Cancer Ther.
- Han, HW;Seo, HH;Jo, HY;Han, HJ;Falcão, VCA;Delorme, V;Heo, J;Shum, D;Choi, JH;Lee, JM;Lee, SH;Heo, HR;Hong, SH;Park, MH;Thimmulappa, RK;Kim, JH; (2019) "Drug Discovery Platform Targeting M. tuberculosis with Human Embryonic Stem Cell-Derived Macrophages." Stem Cell Reports
- Pawar, PP;Odaneth, AA;Vadgama, RN;Lali, AM; (2019) "Simultaneous lipid biosynthesis and recovery for oleaginous yeast Yarrowia lipolytica." Biotechnol Biofuels
- Ambhore, NS;Kalidhindi, RSR;Pabelick, CM;Hawse, JR;Prakash, YS;Sathish, V; (2019) "Differential estrogen-receptor activation regulates extracellular matrix deposition in human airway smooth muscle remodeling via NF-κB pathway." FASEB J.
- Rahn, S;Barbosa, PD;Möller, JL;Ammar, N;Demetrowitsch, T;Helm, O;Wesch, D;Sipos, B;Röcken, C;Schwarz, K;Schäfer, H;Sebens, S; (2019) "Inflammation Associated Pancreatic Tumorigenesis: Upregulation of Succinate Dehydrogenase (Subunit B) Reduces Cell Growth of Pancreatic Ductal Epithelial Cells." Cancers (Basel)
- Cho, H;Shin, I;Cho, K;Yoon, H;Yoo, EK;Kim, MJ;Park, S;Lee, IK;Kim, ND;Sim, T; (2019) "Identification of Novel Resorcinol Amide Derivatives as Potent and Specific Pyruvate Dehydrogenase Kinase (PDHK) Inhibitors." J. Med. Chem.
- An, Z;Liu, P;Zheng, J;Si, C;Li, T;Chen, Y;Ma, T;Zhang, MQ;Zhou, Q;Ding, S; (2019) "Sox2 and Klf4 as the Functional Core in Pluripotency Induction without Exogenous Oct4." Cell Rep
- Schulz, A;Jiang, L;de Vor, L;Ehrström, M;Wermeling, F;Eidsmo, L;Melican, K; (2019) "Neutrophil Recruitment to Noninvasive MRSA at the Stratum Corneum of Human Skin Mediates Transient Colonization." Cell Rep
- Raghu, D;Mobley, RJ;Shendy, NAM;Perry, CH;Abell, AN; (2019) "GALNT3 Maintains the Epithelial State in Trophoblast Stem Cells." Cell Rep
- Colunga, T;Hayworth, M;Kreß, S;Reynolds, DM;Chen, L;Nazor, KL;Baur, J;Singh, AM;Loring, JF;Metzger, M;Dalton, S; (2019) "Human Pluripotent Stem Cell-Derived Multipotent Vascular Progenitors of the Mesothelium Lineage Have Utility in Tissue Engineering and Repair." Cell Rep
- Ko, PJ;Woodrow, C;Dubreuil, MM;Martin, BR;Skouta, R;Bassik, MC;Dixon, SJ; (2019) "A ZDHHC5-GOLGA7 Protein Acyltransferase Complex Promotes Nonapoptotic Cell Death." Cell Chem Biol
- Yang, K;Du, J;Zhang, Z;Liu, D;Ren, T; (2020) "Facile and eco-friendly preparation of super-amphiphilic porous polycaprolactone." J Colloid Interface Sci
- Godet, I;Shin, YJ;Ju, JA;Ye, IC;Wang, G;Gilkes, DM; (2019) "Fate-mapping post-hypoxic tumor cells reveals a ROS-resistant phenotype that promotes metastasis." Nat Commun
- He, L;Wang, H;Han, Y;Wang, K;Dong, H;Li, Y;Shi, D;Li, Y; (2019) "Remodeling of Cellular Surfaces via Fast Disulfide-Thiol Exchange To Regulate Cell Behaviors." ACS Appl Mater Interfaces
- Alaylıoğlu, M;Dursun, E;Yılmazer, S;Gezen-Ak, D; (2019) "TOPOLOGICAL DISTRIBUTION OF STRESS HORMONE RECEPTORS GR AND MR IN RAT BRAIN." Alzheimer's & Dementia
- Rogalsky, A;Musial, T;Molina-Campos, E;Ybarra, N;Bean, L;Voskobiynyk, Y;Russo, M;Nicholson, D; (2019) "HCN CHANNELOPATHY IN THE VENTRAL HIPPOCAMPUS OF ALZHEIMER'S DISEASE MOUSE MODELS." Alzheimer's & Dementia
- Kamen L, Thakurta T, Myneni S, Zheng K, Chung S (2019) "Development of a kinetic antibody-dependent cellular cytotoxicity assay." Journal of Immunological Methods
- I.P. Shanura Fernando, K.K. Asanka Sanjeew, Yong-Seok Ann Chang-ik Kob Seung-Hong Lee, Won Woo Lee, You-Jin Jeon (2018) "Apoptotic and antiproliferative effects of Stigmast-5-en-3-ol from Dendronephthya gigantea on human leukemia HL-60 and human breast cancer MCF-7 cells." Toxicology in Vitro
- Daniel R. McHugh, Miarasa S. Steele, Dana M. Valerio, Alexander Miron, Rachel J. Mann, David F. LePage, Ronald A. Conlon, Calvin U. Cotton, Mitchell L. Drumm, Craig A. Hodges (2018) "A G542X cystic fibrosis mouse model for examining nonsense mutation directed therapies." PLoS ONE
- Andrew J. McKenzie, Stephanie R. Hicks, Kathryn V. Svec, Hannah Naughton, Zöe L. Edmunds & Alan K. Howe (2018) "The mechanical microenvironment regulates ovarian cancer cell morphology, migration, and spheroid disaggregation." Scientific Reports
- R.S.R. Kalidhindi, N.S. Ambhore, M. Thompson, C.M. Pabelick, Y.S. Prakash, S. Venkatachalem (2018) "Role of KISS1/GPR54 Signaling in PDGF Induced Human Airway Smooth Muscle Remodeling." American Journal of Respiratory and Critical Care Medicine
- Ju-HyeYang, Jae-MyungYoo, Esther Lee, Bo Hyoung Lee, Won-Kyung ChoKwang-Il, Park Jin, Yeul Ma (2018-01-30) "Anti-inflammatory effects of Perillae Herba ethanolic extract against TNF-α/IFN-γ-stimulated human keratinocyte HaCaT cells." Journal of Ethnopharmacology
- I. P. Shanura Fernand,o K. K. Asanka Sanjeewa, Hyun‐Soo Kim, Lei Wang, Won Woo Lee, You‐Jin Jeon (2017) "Apoptotic and antiproliferative properties of 3β‐hydroxy‐Δ5‐steroidal congeners from a partially purified column fraction of Dendronephthya gigantea against HL‐60 and MCF‐7 cancer cells." Journal of Applied Toxicology
- K Parratt, J Jeong, P Qiu, K Roy (2017) "3D material cytometry (3DMaC): a very high-replicate, high-throughput analytical method using microfabricated, shape-specific, cell-material niches." Lab on a Chip
- Angela K. Berger, Hong Yi, Daniel B. Kearns, Bernardo A. Mainou (2017) "Bacteria and bacterial envelope components enhance mammalian reovirus thermostability." PLoS Pathog
- Mary C. Drinane, Usman Yaqoob, Haibin Yu, Fanghong Luo, Thomas Greuter, Juan P. Arab, Enis Kostallari, Vikas K. Verma, Jessica Maiers, Thiago Milech De Assuncao, Michael Simons, Debabrata Mukhopadhyay, Tatiana Kisseleva, David A. Brenner, Raul Urrutia, Gwen Lomberk, Yandong Gao, Giovanni Ligresti, Daniel J. Tschumperlin, Alexander Revzin, Sheng Cao, and Vijay H. Shah (2017) "Synectin promotes fibrogenesis by regulating PDGFR isoforms through distinct mechanisms." JCI Insight
- Ahasan Habib, Venkatachalem Sathish, Sanku Mallik, Bashir Khoda (2018) "3D Printability of Alginate-Carboxymethyl Cellulose Hydrogel." Materials
- Kristine Østevold, Ana V. Meléndez, Friederike Lehmann,1,3,4 Gudula Schmidt, Klaus Aktories, and Carsten Schwan (2017) "Septin remodeling is essential for the formation of cell membrane protrusions (microtentacles) in detached tumor cells." Oncotarget
- Judy J. Brown, Sarah P. Short, Jennifer Stencel-Baerenwald, Kelly Urbanek, Andrea J. Pruijssers, Nicole McAllister, Mine Ikizler, Gwen Taylor, Pavithra Aravamudhan, Solomiia Khomandiak, Bana Jabri, Christopher S. Williams, Terence S. Dermody (2018) "Reovirus-Induced Apoptosis in the Intestine Limits Establishment of Enteric Infection." Journal of Virology
- Sánchez-Valdéz, FJ;Padilla, A;Wang, W;Orr, D;Tarleton, RL; (2017) "Spontaneous dormancy protects Trypanosoma cruzi during extended drug exposure." bioRxiv
科学期刊
商务期刊
Genetic Engineering & Biotechnology News (1)
科学海报
- Consistent, Repeatable Wound Healing Assays Incorporating a Novel, Automated Scratch Tool and Kinetic Label-Free Imaging (February 6, 2019)
- Advanced 2D Wound Healing Assay Procedures Performed using a Novel, Automated Scratch Tool, High Contrast Brightfield and Fluorescence Kinetic Imaging (February 6, 2019)
- Quantitative Microscopy of Angiogenesis in Zebrafish Embryos (February 6, 2019)
- Automated Analysis of Neutrophil NETosis Activity (February 6, 2019)
- Monitoring Cellular Stress Response and Inhibition of GPCR-Dependent Calcium Signaling Using Expressed Biosensors (December 9, 2018)
- Autophagy Analysis Using Object Spot Counting (February 5, 2018)
- Evaluating Ethanol Induced Cell Death in Zebrafish (February 5, 2018)
- Automated imaging-based technique for monitoring of Ca2+ and DAG biosensors enables detailed characterization of GPCR kinetics (December 4, 2017)
- Characterizing GPCR Activation Using Automated Live Cell Imaging (February 13, 2017)
技术注释
动态摘要
- Analysis of RelA Nuclear Translocation (January 9, 2020)
- Rapid Cytotoxicity Determination in 384-well Microplates with Wide Field of View Camera (September 5, 2019)
- Quantitative Multiplexed Imaging of Mixed Bacteria (May 22, 2019)
- Characterizing Both Rapid and Long-Term Treatment Effects Using Expressed Biosensors and Automated Live-Cell Imaging (May 3, 2019)
- Automated Analysis of Neutrophil Netosis (April 25, 2019)
- Analyzing Tail Fin Regeneration in Zebrafish Embryos (March 12, 2019)
- Analyzing Angiogenesis in Zebrafish Embryos (March 5, 2019)
- Quantifying Morphological Changes in Zebrafish Embryos Exposed to Toxins (January 30, 2019)
- 3D Kinetic NK Cell Cytotoxicity Assay (November 13, 2018)
- Automatic Transfection Efficiency Calculation in Microplates (November 13, 2018)
- Color Brightfield Imaging H&E Stained Tissue (November 13, 2018)
- Comet Assay: Single Cell Genotoxicity Measurement (November 13, 2018)
- Automated Wound Creation for Scratch Wound Healing Assays (November 13, 2018)
- Quantifying Poly-Glutamine Aggregates in C. Elegans Using vivoChip (August 24, 2018)
- Automated Cell Fixing, Staining and Immunofluorescence in Microplates (August 3, 2018)
- Counting Caenorhabditis Elegans in 96-Well Plates (July 31, 2018)
- Label-Free Tumor Invasion Assay Using 3D Tumor Spheroids (June 19, 2018)
- High Resolution Imaging of Cells Undergoing Mitosis in Microplates (April 6, 2018)
- High Throughput Cell Migration Assay (April 5, 2018)
- Direct Fluorescence Assay (DFA) (April 2, 2018)
- Measuring Apoptosis in Zebrafish Treated with Ethanol (March 26, 2018)
- Quantifying Cancer Biomarker Gene Expression Using RNA FISH (March 21, 2018)
- Live Cell Imaging of Apoptosis and Necrosis (March 20, 2018)
- Gram Stain Imaging (March 19, 2018)
- Acid Fast Bacteria (AFB) Scoring (March 19, 2018)
- Kinetic Characterization of Gs- and Gi-Dependent Regulation of cAMP (February 16, 2018)
- γH2AX Foci Spot Counting as a Determination of Genotoxicity (February 16, 2018)
- Phagocytosis Assay (February 16, 2018)
- Imaging and Quantification of T Cell Mediated Cytotoxicity (December 7, 2017)
- Image-Based Tracking and Quantification of T Cell Activation (December 7, 2017)
- Cell Proliferation - Label-free Confluence (November 15, 2017)
- Non-Alcoholic Steatohepatitis (NASH) Imaging Assay (November 6, 2017)
- Mitochondrial Membrane Potential Analysis Using Object Spot Counting (August 4, 2017)
- Sub-Micron Spot Quantitation of Centromeres (July 28, 2017)
- Kinetic Cytotoxicity Using Cell Counting (June 16, 2017)
- Autophagy Analysis Using Object Spot Counting (June 14, 2017)
- Cell Migration Assay: 3D Bioprinting (May 4, 2017)
- Calcium Kinetics (April 28, 2017)
- Plaque Assay (February 24, 2017)
网络视频
- Zebrafish Imaging with Quantitative Analysis - On Demand (March 20, 2019)
- Image Analysis 101 - Case Studies in Microbiology - On Demand (November 7, 2018)
- Quantitative Intracellular and Intranuclear Spot Analysis Using Digital Microscopy (November 29, 2017)
- Enabling Quantitative Cellular Imaging (November 29, 2016)
- Automated Live Cell Imaging (May 26, 2016)