Resources
应用指南
应用手册
- Image Analysis of Herpesvirales Specificity Challenge using Direct Fluorescence Antibody Assay (DFA) (December 10, 2020)
- Automated Scoring of Acid-fast Bacteria (AFB) by Fluorescent Smear Microscopy (October 16, 2019)
- Nuclear Translocation of RelA in Stimulated Macrophages (September 18, 2019)
- Automated Analysis of Neutrophil NETosis Activity (April 30, 2019)
- Analyzing Wound Healing in Zebrafish Embryos (February 11, 2019)
- Automated Image Screening of Zebrafish Embryos Exposed to Developmental Toxins (January 4, 2019)
- Quantitative Microscopy of Angiogenesis in Zebrafish Embryos (December 6, 2018)
- Determination of Cell Cycle Time (December 6, 2018)
- Advanced Wound Healing Assay Workflow using Automated Scratch Wound Creation, High Contrast Brightfield and Fluorescence Kinetic Imaging (December 6, 2018)
- Thapsigargin-induced Cellular Stress Response and Inhibition of Gq-dependent Calcium Signaling (October 5, 2018)
- Characterizing Gs- and Gi-dependent Regulation of cAMP Levels in Real Time with cADDis Biosensor and Automated Live Cell Imaging (March 29, 2018)
- Stimulation of IL-2 Secretion in Human Lymphocytes (March 21, 2018)
- Using Acridine Orange to Measure Cell Death in Ethanol Treated Zebrafish Embryos (December 27, 2017)
- Brightfield and Fluorescence Imaging using 3D PrimeSurface® Ultra-Low Attachment Microplates (December 21, 2017)
- Automated Imaging Assay for Characterizing Ca2+ Flux with R-GECO Biosensor (September 28, 2017)
- Mitochondrial Membrane Potential by Object Spot Counting (September 11, 2017)
- Lipid Accumulation in HepG2 Cells Exposed to Free Fatty Acids (August 14, 2017)
- Comparison of Different Cell Types for Neutral Lipid Accumulation (August 14, 2017)
- Automation of Non-Alcoholic Fatty Liver Disease Model Assay (August 14, 2017)
- Autophagy Analysis Using Object Spot Counting (July 11, 2017)
- Characterizing Calcium Mobilization using Kinetic Live Cell Imaging (January 26, 2017)
- Monitoring Saccharomyces cerevisiea Growth with Brightfield Microscopy in Real Time (July 20, 2016)
- Performance of a Label-Free Image-Based 2D Scratch Wound Healing Assay to monitor Cell Migration and its Inhibition (June 29, 2016)
- Oridonin Perfusion Causes Cytotoxicity in U-2 OS Cells (June 29, 2016)
引用文献
细胞成像&显微镜
Lionheart FX Automated Microscope (149)
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- Inde, ZR; (2020) "Molecular Origins of Heterogeneity in Cancer Cell Death." Thesis
- Ando, S;Otsu, W;Osanai, D;Kamiya, S;Ishida, K; (2020) "Survival Motor Neuron Protein Modulates Lysosomal Function Through the Expression of Transcription Factor EB in Motoneurons." BPB Reports
- Almashjary, MN; (2020) "The Impact of Dietary Iron Restriction on Sickling Kinetics and Hemolysis in a Transgenic Model of Sickle Cell Disease." Thesis
- Sun, Q;Kim, OS;He, Y;Lim, W;Ma, G;Kim, B;Kim, Y;Kim, O; (2020) "Role of E2F1/SPHK1 and HSP27 During Irradiation in a PMA-Induced Inflammatory Model." Photobiomodul Photomed Laser Surg
- Thamm, K;Möbus, K;Towers, R;Segeletz, S;Wetzel, R;Bornhäuser, M;Zhang, Y;Wobus, M; (2020) "A Novel Synthetic, Xeno-Free Biomimetic Surface for Serum-Free Expansion of Human Mesenchymal Stromal Cells." Adv Biosyst
- Samaraweera, AV;Liyanage, DS;Omeka, WKM;Yang, H;Priyathilaka, TT;Lee, J; (2020) "Molecular insights into peroxiredoxin 4 (HaPrx4) from the big-belly seahorse (Hippocampus abdominalis): Molecular characteristics, functional activity and transcriptional responses against immune stimulants." Comp. Biochem. Physiol. B, Biochem. Mol. Biol.
- Liu, L;Fang, R;Wei, Z;Wu, J;Li, X;Li, W; (2020) "Giardia duodenalis Induces Apoptosis in Intestinal Epithelial Cells via Reactive Oxygen Species-Mediated Mitochondrial Pathway In Vitro." Pathogens (Basel, Switzerland)
- Fuchs, HR;Meister, R;Lotke, R;Framme, C; (2020) "The microRNAs miR-302d and miR-93 inhibit TGFB-mediated EMT and VEGFA secretion from ARPE-19 cells." Exp. Eye Res.
- An, JH;Park, SY;Kim, GH;Mo, IP;Kim, S;Woo, HM;Park, KM; (2020) "Tissue engineered ultra-thin descemet stripping corneal endothelial layers using porcine cornea and stem cells." Exp. Eye Res.
- Turn, RE;East, MP;Prekeris, R;Kahn, RA; (2020) "The ARF GAP ELMOD2 acts with different GTPases to regulate centrosomal microtubule nucleation and cytokinesis." Mol. Biol. Cell
- Deng, L;Chen, J;Wang, T;Chen, B;Yang, L;Liao, J;Chen, Y;Wang, J;Tang, H;Yi, J;Kang, K;Li, L;Gou, D; (2020) "PDGF/MEK/ERK Axis represses Ca2+ clearance via Decreasing the Abundance of Plasma Membrane Ca2+ Pump PMCA4 in Pulmonary Arterial Smooth Muscle Cells." Am. J. Physiol., Cell Physiol.
- Rosati, R;Romeo, L;Silvestri, S;Marcheggiani, F;Tiano, L;Frontoni, E; (2020) "Faster R-CNN approach for detection and quantification of DNA damage in comet assay images." Comput. Biol. Med.
- Şengül, B;Dursun, E;Verkhratsky, A;Gezen-Ak, D; (2020) "Overexpression of α-Synuclein Reorganises Growth Factor Profile of Human Astrocytes." Mol. Neurobiol.
- Kondrateva, E;Adilgereeva, E;Amelina, E;Tabakov, V;Demchenko, A;Ustinov, K;Yasinovsky, M;Voronina, E;Lavrov, A;Smirnikhina, S; (2020) "Generation of induced pluripotent stem cell line (RCMGi001-A) from human skin fibroblasts of a cystic fibrosis patient with p.F508del mutation." Stem cell research
- Shendy, NAM;Raghu, D;Roy, S;Perry, CH;Safi, A;Branco, MR;Homayouni, R;Abell, AN; (2020) "Coordinated regulation of Rel expression by MAP3K4, CBP, and HDAC6 controls phenotypic switching." Commun Biol
- Berry, JTL;Muñoz, LE;Rodríguez Stewart, RM;Selvaraj, P;Mainou, BA; (2020) "Doxorubicin Conjugation to Reovirus Improves Oncolytic Efficacy in Triple-Negative Breast Cancer." Molecular therapy oncolytics
- Wu, J;Li, L;Jiang, G;Zhan, H;Zhu, X;Yang, W; (2020) "NCAPG2 facilitates glioblastoma cells\' malignancy and xenograft tumor growth via HBO1 activation by phosphorylation." Cell Tissue Res.
- Seo, HH;Han, HW;Lee, SE;Hong, SH;Cho, SH;Kim, SC;Koo, SK;Kim, JH; (2020) "Modelling Toxoplasma gondii infection in human cerebral organoids." Emerg Microbes Infect
- Margraf, A;Cappenberg, A;Vadillo, E;Ludwig, N;Thomas, K;Körner, K;Zondler, L;Rossaint, J;Germena, G;Hirsch, E;Zarbock, A; (2020) "ArhGAP15, a RacGAP, Acts as a Temporal Signaling Regulator of Mac-1 Affinity in Sterile Inflammation." J. Immunol.
- Shao, C;Lu, W;Du, Y;Yan, W;Bao, Q;Tian, Y;Wang, G;Ye, H;Hao, H; (2020) "Cytosolic ME1 integrated with mitochondrial IDH2 supports tumor growth and metastasis." Redox Biol
- Inde, Z;Forcina, GC;Denton, K;Dixon, SJ; (2020) "Kinetic Heterogeneity of Cancer Cell Fractional Killing." Cell Rep
- Yang, W;Liu, S;Li, Y;Wang, Y;Deng, Y;Sun, W;Huang, H;Xie, J;He, A;Chen, H;Tao, A;Yan, J; (2020) "Pyridoxine induces monocyte-macrophages death as specific treatment of acute myeloid leukemia." Cancer Lett.
- Lee, SW;Kim, J;Do, M;Namkoong, E;Lee, H;Ryu, JH;Park, K; (2020) "Developmental role of hyaluronic acid and its application in salivary gland tissue engineering." Acta Biomater
- Wolfarth, AA;Liu, X;Darby, TM;Boyer, DJ;Spizman, JB;Owens, JA;Chandrasekharan, B;Naudin, CR;Hanley, KZ;Robinson, BS;Ortlund, EA;Jones, RM;Neish, AS; (2020) "Proline-Rich Acidic Protein 1 (PRAP1) Protects the Gastrointestinal Epithelium From Irradiation-Induced Apoptosis." Cellular and molecular gastroenterology and hepatology
- Becker, L;Verdurmen, WPR;Plückthun, A; (2020) "Reengineering anthrax toxin protective antigen for improved receptor-specific protein delivery." BMC Biol.
- Kang, JH;Ko, HM;Han, GD;Lee, SY;Moon, JS;Kim, MS;Koh, JT;Kim, SH; (2020) "Dual role of phosphatidylserine and its receptors in osteoclastogenesis." Cell Death Dis
- Martinez-Carrasco, R;Argüeso, P;Fini, ME; (2020) "Dynasore protects ocular surface mucosal epithelia subjected to oxidative stress by maintaining UPR and calcium homeostasis." Free radical biology & medicine
- Lyu, Y;Kopcho, S;Alvarez, FA;Okeoma, BC;Okeoma, CM; (2020) "Development of a Cationic Amphiphilic Helical Peptidomimetic (B18L) As A Novel Anti-Cancer Drug Lead." Cancers
- Ruchi P. Patel, Skyler Kuhn, Da Yin, Jordan Hotz, Frances A. Maher,a Robert W. Robey, Michael M. Gottesman, Sachi Horibata (2021) "Cross-resistance of cisplatin selected cells to anti-microtubule agents: Role of general survival mechanisms." Transl Oncol
- Zhao, B;Xu, P;Rowlett, CM;Jing, T;Shinde, O;Lei, Y;West, AP;Liu, WR;Li, P; (2020) "The Molecular Basis of Tight Nuclear Tethering and Inactivation of cGAS." Nature
- Haniff, HS;Knerr, L;Liu, X;Crynen, G;Boström, J;Abegg, D;Adibekian, A;Lekah, E;Wang, KW;Cameron, MD;Yildirim, I;Lemurell, M;Disney, MD; (2020) "Design of a small molecule that stimulates vascular endothelial growth factor A enabled by screening RNA fold-small molecule interactions." Nature chemistry
- Zhang, L;Avery, J;Yin, A;Singh, AM;Cliff, TS;Yin, H;Dalton, S; (2020) "Generation of Functional Brown Adipocytes from Human Pluripotent Stem Cells via Progression through a Paraxial Mesoderm State." Cell Stem Cell
- Sun, Y;Eshov, A;Zhou, J;Isiktas, AU;Guo, JU; (2020) "C9orf72 arginine-rich dipeptide repeats inhibit UPF1-mediated RNA decay via translational repression." Nat Commun
- Huang, C;Ho, J;Chiang, J;Yu, C;Yu, D; (2020) "Exosome-transmitted LINC00960 and LINC02470 promote the epithelial-mesenchymal transition and aggressiveness of bladder cancer cells." Research Square
- Kim, S;Choi, H;Kim, J;Lee, D; (2020) "The Antiasthma Medication Ciclesonide Suppresses Breast Cancer Stem Cells through Inhibition of the Glucocorticoid Receptor Signaling-dependent YAP Pathway." Research Square
- Wright, W;Yang, L;Chen, T; (2020) "Detection of endogenous and drug-modulated CYP3A activity in cells using LC-MS/MS." Research Square
- Johnson, HC; (2020) "Integrative Click Chemistry for Tuning Physicochemical Properties of Cancer Cell-Laden Hydrogels." Thesis
- Hernandez, J;Beaty, D;Fruhwirth, L;Sloan, J;Chaves, A;Riordan, N; (2020) "Dodging COVID-19 infection: Low expression and localization of Angiotensin-Converting Enzyme 2 (ACE2) and Transmembrane Serine Protease 2 (TMPRSS2) in Mesenchymal Stem Cells derived from human umbilical cord (hUC-MSCs).." Research Square
- Pedrioli, G;Barberis, M;Molinari, M;Morone, D;Papin, S;Paganetti, P; (2020) "Extracellular Vesicles Hijack the Autophagic Pathway to Induce Tau Accumulation in Endolysosomes." bioRxiv
- Tandon, R;Mitra, D;Sharma, P;Stray, S;Bates, J;Marshall, G; (2020) "Effective Screening of SARS-CoV-2 Neutralizing Antibodies in Patient Serum using Lentivirus Particles Pseudotyped with SARS-CoV-2 Spike Glycoprotein." medRxiv
- Jang, WB;Ji, ST;Park, JH;Kim, YJ;Kang, S;Kim, DY;Lee, NK;Kim, JS;Lim, HJ;Choi, J;Le, THV;Ly, TTG;Rethineswaran, VK;Kim, DH;Ha, JS;Yun, J;Baek, SH;Kwon, SM; (2020) "Engineered M13 Peptide Carrier Promotes Angiogenic Potential of Patient-Derived Human Cardiac Progenitor Cells and In Vivo Engraftment." Tissue Eng Regen Med
- Zhou, K;Goodman, CL;Ringbauer, JA;Stanley, D; (2020) "Cell lines derived from the western corn rootworm larvae, Diabrotica virgifera virgifera (Chrysomelidae: Coleoptera)." In Vitro Cell. Dev. Biol. Anim.
- Tandon, R;Sharp, JS;Zhang, F;Pomin, VH;Ashpole, NM;Mitra, D;Jin, W;Liu, H;Sharma, P;Linhardt, RJ; (2020) "Effective Inhibition of SARS-CoV-2 Entry by Heparin and Enoxaparin Derivatives." bioRxiv
- Sola, M;Magrin, C;Pedrioli, G;Pinton, S;Salvadè, A;Papin, S;Paganetti, P; (2020) "Tau affects P53 function and cell fate during the DNA damage response." Commun Biol
- Kalidhindi, RSR;Borkar, NA;Ambhore, NS; (2020) "Kisspeptins Regulate Human Airway Smooth Muscle Cell Proliferation and Remodeling." B108 NEW INSIGHTS INTO AIRWAY REMODELLING AND REPAIR
- Lim, MH;Jeun, JH;Kim, DH;Park, SH;Kim, SJ;Lee, WS;Hwang, SH;Lim, JY;Kim, SW; (2020) "Evaluation of Collagen Gel-Associated Human Nasal Septum-Derived Chondrocytes As a Clinically Applicable Injectable Therapeutic Agent for Cartilage Repair." Tissue Eng Regen Med
- Liu, Z;Anderson, JD;Deng, L;Mackay, S;Bailey, J;Kersh, L;Rowe, SM;Guimbellot, JS; (2020) "Human Nasal Epithelial Organoids for Therapeutic Development in Cystic Fibrosis." Genes (Basel)
- Kwak, J;Kim, K; (2020) "Enhancing immunogenicity of a reporter protein by fusion to glycoprotein and nucleoprotein of viral hemorrhagic septicemia virus (VHSV) particles." Fish & Shellfish Immunology
- Zondervan, RL;Jenkins, DC;Reicha, JD;Hankenson, KD; (2020) "Thrombospondin-2 spatiotemporal expression in skeletal fractures." J. Orthop. Res.
- Lee, MN;Song, JH;Oh, SH;Tham, NT;Kim, JW;Yang, JW;Kim, ES;Koh, JT; (2020) "The primary cilium directs osteopontin-induced migration of mesenchymal stem cells by regulating CD44 signaling and Cdc42 activation." Stem Cell Res
- Seo, Y;Choi, J;Lee, JH;Kim, TG;Park, SH;Han, G;Namkung, W;Kim, I; (2020) "Diversity-oriented generation and biological evaluation of new chemical scaffolds bearing a 2,2-dimethyl-2H-chromene unit: Discovery of novel potent ANO1 inhibitors." Bioorg. Chem.
- Ling, T;Hadi, V;Bollinger, J;Rivas, F; (2020) "Identification of rapid access to polycyclic systems via a base-catalyzed cascade cyclization reaction and their biological evaluation." Bioorg. Chem.
- Zheng, P;Su, Q;Jin, D;Yu, Y;Huang, X; (2020) "Prevention of Neurite Spine Loss Induced by Dopamine D2 Receptor Overactivation in Striatal Neurons." Front. Neurosci.
- Eccardt, AM;Pelzel, RJ;Mattathil, L;Moon, YA;Mannino, MH;Janowiak, BE;Fisher, JS; (2020) "A peroxidase mimetic protects skeletal muscle cells from peroxide challenge and stimulates insulin signaling." Am. J. Physiol., Cell Physiol.
- Suryawanshi, RK;Koujah, L;Patil, CD;Ames, JM;Agelidis, A;Yadavalli, T;Patil, SV;Shukla, D; (2020) "Bacterial Pigment Prodigiosin Demonstrates a Unique Antiherpesvirus Activity That Is Mediated through Inhibition of Prosurvival Signal Transducers." J. Virol.
- Dhall, S;Lerch, A;Johnson, N;Jacob, V;Jones, B;Park, MS;Sathyamoorthy, M; (2020) "A Flowable Placental Formulation Prevents Bleomycin-Induced Dermal Fibrosis in Aged Mice." Int J Mol Sci
- Hannon, G;Bogdanska, A;Volkov, Y;Prina-Mello, A; (2020) "Comparing the Effects of Intracellular and Extracellular Magnetic Hyperthermia on the Viability of BxPC-3 Cells." Nanomaterials (Basel)
- Demirci, S;Gudmundsdottir, B;Li, Q;Haro-Mora, JJ;Nassehi, T;Drysdale, C;Yapundich, M;Gamer, J;Seifuddin, F;Tisdale, JF;Uchida, N; (2020) "βT87Q-Globin Gene Therapy Reduces Sickle Hemoglobin Production, Allowing for Ex Vivo Anti-sickling Activity in Human Erythroid Cells." Mol Ther Methods Clin Dev
- Jang, YG;Ko, EB;Choi, KC; (2020) "Gallic acid, a phenolic acid, hinders the progression of prostate cancer by inhibition of histone deacetylase 1 and 2 expression." J. Nutr. Biochem.
- Huang, CS;Ho, JY;Chiang, JH;Yu, CP;Yu, DS; (2020) "Exosome-Derived LINC00960 and LINC02470 Promote the Epithelial-Mesenchymal Transition and Aggressiveness of Bladder Cancer Cells." Cells
- Guo, Y;Li, H;Chen, X;Yang, H;Guan, H;He, X;Chen, Y;Pokharel, S;Xiao, H;Li, Y; (2020) "Novel Roles of Chloroquine and Hydroxychloroquine in Graves\' Orbitopathy Therapy by Targeting Orbital Fibroblasts." J. Clin. Endocrinol. Metab.
- Yadav, VK;Huang, YJ;George, TA;Wei, PL;Sumitra, MR;Ho, CL;Chang, TH;Wu, ATH;Huang, HS; (2020) "Preclinical Evaluation of the Novel Small-Molecule MSI-N1014 for Treating Drug-Resistant Colon Cancer via the LGR5/β-catenin/miR-142-3p Network and Reducing Cancer-Associated Fibroblast Transformation." Cancers (Basel)
- Kim, SK;Jang, SD;Kim, H;Chung, S;Park, JK;Kuh, HJ; (2020) "Phenotypic Heterogeneity and Plasticity of Cancer Cell Migration in a Pancreatic Tumor Three-Dimensional Culture Model." Cancers (Basel)
- Meinhardt, G;Haider, S;Kunihs, V;Saleh, L;Pollheimer, J;Fiala, C;Hetey, S;Feher, Z;Szilagyi, A;Than, NG;Knöfler, M; (2020) "Pivotal role of the transcriptional co-activator YAP in trophoblast stemness of the developing human placenta." Proc. Natl. Acad. Sci. U.S.A.
- Liu, Y;Han, Y;Fang, T;Chen, SM;Hu, X;Song, L;Shen, H;Dong, H;Jiang, YY;Zou, Z;Li, Y;An, MM; (2020) "Turning weakness into strength: Albumin nanoparticle-redirected amphotericin B biodistribution for reducing nephrotoxicity and enhancing antifungal activity." J Control Release
- Gerasimaite, R;Seikowski, J;Schimpfhauser, J; (2020) "Overcoming efflux of fluorescent probes for actin imaging in living cells." bioRxiv
- Cousminer, DL;Wagley, Y;Pippin, J;Elhakeem, A; (2020) "Genome-wide association study implicates novel loci and reveals candidate effector genes for longitudinal pediatric bone accrual through variant-to-gene mapping." medRxiv
- Perdue, LA;Do, P;David, C;Chyong, A;Kellner, A; (2020) "Optical Control of Cytokine Signaling via Bioinspired, Polymer-Induced Latency." bioRxiv
- Negro, G;Aschenbrenner, B;Brezar, SK;Cemazar, M;Coer, A;Gasljevic, G;Savic, D;Sorokin, M;Buzdin, A;Callari, M;Kvitsaridze, I;Jewett, A;Vasileva-Slaveva, M;Ganswindt, U;Skvortsova, I;Skvortsov, S; (2020) "Molecular heterogeneity in breast carcinoma cells with increased invasive capacities." Radiol Oncol
- Ghahramani, M;Yousefi, R;Niazi, A;Kurganov, B; (2020) "The congenital cataract-causing mutations P20R and A171T are associated with important changes in the amyloidogenic feature, structure and chaperone-like activity of human αB-crystallin." Biopolymers
- Banks, P;Beckman, S; (2020) "Assessing Phenotypic Changes in Zebrafish through Automated Quantitative Imaging." Genetic Engineering & Biotechnology News
- Inde, Z;Forcina, GC;Denton, K;Dixon, SJ; (2020) "Large-Scale Analysis of Cell Death Phenotypic Heterogeneity." bioRxiv
- Akbarian, M;Tayebi, L;Mohammadi-Samani, S;Farjadian, F; (2020) "Mechanistic Assessment of Functionalized Mesoporous Silica-Mediated Insulin Fibrillation." J Phys Chem B
- Meegan, JE;Shaver, CM;Putz, ND;Jesse, JJ;Landstreet, SR;Lee, HNR;Sidorova, TN;McNeil, JB;Wynn, JL;Cheung-Flynn, J;Komalavilas, P;Brophy, CM;Ware, LB;Bastarache, JA; (2020) "Cell-free hemoglobin increases inflammation, lung apoptosis, and microvascular permeability in murine polymicrobial sepsis." PLoS ONE
- Chda, A;El Kabbaoui, M;Fresco, P;Silva, D;Gonçalves, J;Oliveira, AP;Andrade, PB;Valentão, P;Tazi, A;El Abida, K;Bencheikh, R; (2020) "Centaurium Erythraea Extracts Exert Vascular Effects through Endothelium- and Fibroblast-dependent Pathways." Planta Med.
- Otsu, W;Ishida, K;Nakamura, S;Shimazawa, M;Tsusaki, H;Hara, H; (2020) "Blue light-emitting diode irradiation promotes transcription factor EB-mediated lysosome biogenesis and lysosomal cell death in murine photoreceptor-derived cells." Biochem. Biophys. Res. Commun.
- Zhou, Z;Song, X;Chi, JJ;Gius, DR;Huang, Y;Cristofanilli, M;Wan, Y; (2020) "Regulation of KLF4 by posttranslational modification circuitry in endocrine resistance." Cell. Signal.
- White-Gilbertson, S;Lu, P;Jones, CM;Chiodini, S;Hurley, D;Das, A;Delaney, JR;Norris, JS;Voelkel-Johnson, C; (2020) "Tamoxifen is a candidate first-in-class inhibitor of acid ceramidase that reduces amitotic division in polyploid giant cancer cells-Unrecognized players in tumorigenesis." Cancer Med
- Jeon, BH;Yoo, YM;Jung, EM;Jeung, EB; (2020) "Dexamethasone Treatment Increases the Intracellular Calcium Level Through TRPV6 in A549 Cells." Int J Mol Sci
- Choi, HS;Kim, SL;Kim, JH;Lee, DS; (2020) "The FDA-Approved Anti-Asthma Medicine Ciclesonide Inhibits Lung Cancer Stem Cells through Hedgehog Signaling-Mediated SOX2 Regulation." Int J Mol Sci
- Lee, HG;Lu, YA;Li, X;Hyun, JM;Kim, HS;Lee, JJ;Kim, TH;Kim, HM;Kang, MC;Jeon, AY; (2020) "Anti-Obesity Effects of Grateloupia elliptica, a Red Seaweed, in Mice with High-Fat Diet-Induced Obesity via Suppression of Adipogenic Factors in White Adipose Tissue and Increased Thermogenic Factors in Brown Adipose Tissue." Nutrients
- Melo, AM;Conroy, MJ;Foley, EK;Dockry, É;Breen, EP;Reynolds, JV;Lysaght, J;Doherty, DG; (2020) "CD1d expression and invariant natural killer T-cell numbers are reduced in patients with upper gastrointestinal cancers and are further impaired by commonly used chemotherapies." Cancer Immunol. Immunother.
- Liu, YC;Wang, HL;Huang, YZ;Weng, YH;Chen, RS;Tsai, WC;Yeh, TH;Lu, CS;Chen, YL;Lin, YW;Chen, YJ;Hsu, CC;Chiu, CH;Chiu, CC; (2020) "Alda-1, an activator of ALDH2, ameliorates Achilles tendinopathy in cellular and mouse models." Biochem. Pharmacol.
- Wright, WC;Chenge, J;Wang, J;Girvan, HM;Yang, L;Chai, SC;Huber, AD;Wu, J;Oladimeji, PO;Munro, AW;Chen, T; (2020) "Clobetasol Propionate Is a Heme-Mediated Selective Inhibitor of Human Cytochrome P450 3A5." J. Med. Chem.
- Wei, M;Haney, MG;Rivas, DR;Blackburn, JS; (2020) "Protein tyrosine phosphatase 4A3 (PTP4A3/PRL-3) drives migration and progression of T-cell acute lymphoblastic leukemia in vitro and in vivo." Oncogenesis
- Rodrigues, DF;Pires das Neves, R;Carvalho, ATP;Lourdes Bastos, M;Costa, VM;Carvalho, F; (2020) "In vitro mechanistic studies on α-amanitin and its putative antidotes." Arch. Toxicol.
- Liu, J;Cai, Q;Wang, W;Lu, M;Liu, J;Zhou, F;Sun, M;Wang, G;Zhang, J; (2020) "Ginsenoside Rh2 pretreatment and withdrawal reactivated the pentose phosphate pathway to ameliorate intracellular redox disturbance and promoted intratumoral penetration of adriamycin." Redox Biol
- Aravamudhan, P;Raghunathan, K;Konopka-Anstadt, J;Pathak, A;Sutherland, DM;Carter, BD;Dermody, TS; (2020) "Reovirus uses macropinocytosis-mediated entry and fast axonal transport to infect neurons." PLoS Pathog.
- Nam, KC;Han, YS;Lee, JM;Kim, SC;Cho, G;Park, BJ; (2020) "Photo-Functionalized Magnetic Nanoparticles as a Nanocarrier of Photodynamic Anticancer Agent for Biomedical Theragnostics." Cancers (Basel)
- Mehta, S;McKinney, C;Algie, M;Verma, CS;Kannan, S;Harfoot, R;Bartolec, TK;Bhatia, P;Fisher, AJ;Gould, ML;Parker, K;Cesare, AJ;Cunliffe, HE;Cohen, SB;Kleffmann, T;Braithwaite, AW;Woolley, AG; (2020) "Dephosphorylation of YB-1 is Required for Nuclear Localisation During G2 Phase of the Cell Cycle." Cancers (Basel)
- Yoo, J;Yun, C;Bui, N;Oh, J;Nam, S; (2019) "Photoacoustic Monitoring of the Viability of Mesenchymal Stem Cells Labeled with Indocyanine Green." IRBM
- Afzal, A;Figueroa, EE;Kharade, SV;Bittman, K;Matlock, BK;Flaherty, DK;Denton, JS; (2019) "The LRRC8 volume-regulated anion channel inhibitor, DCPIB, inhibits mitochondrial respiration independently of the channel." Physiol Rep
- Prekovic, S;Schuurman, K;Manjon, AG;Buijs, M; (2019) "Glucocorticoids regulate cancer cell dormancy." bioRxiv
- Jung, E;Yoo, Y;Park, SY;Ahn, C;Jeon, B;Hong, E;Jeung, WK; (2019) "Calbindin-D9k is a novel risk gene for neurodegenerative disease.." assets.researchsquare.com
- Raghu, D; (2019) "GALNT3 Maintains the Epithelial State by Promoting O-Galnac Modification of E-Cadherin in Trophoblast Stem Cells and Human Mammary Epithelial Cells." Thesis
- Tanuja Koppal (2020) "Innovations in Cell Counting." Biocompare
- Zilberman-Itskovich, S;Abu-Hamad, R;Zarura, R;Sova, M;Hachmo, Y;Stark, M;Neuman, S;Slavin, S;Efrati, S; (2019) "Human mesenchymal stromal cells ameliorate complement induced inflammatory cascade and improve renal functions in a rat model of ischemia-reperfusion induced acute kidney injury." PLoS ONE
- Liu, S;Liu, H;Zhang, K;Li, X;Duan, Y;Wang, Z;Wang, T; (2019) "Proteasome Inhibitor PS-341 Effectively Blocks Infection by the Severe Fever with Thrombocytopenia Syndrome Virus." Virol Sin
- Kang, S;Cho, H;Jeon, D;Park, S;Shin, D;Heo, C; (2019) "A Matrix Metalloproteinase Sensing Biosensor for the Evaluation of Chronic Wounds." BioChip J
- Beal, EW;Kim, JL;Reader, BF;Akateh, C;Maynard, K;Washburn, WK;Zweier, JL;Whitson, BA;Black, SM; (2019) "[D-Ala2, D-Leu5] Enkephalin Improves Liver Preservation During Normothermic Ex Vivo Perfusion." J. Surg. Res.
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- Sharma, N;Dev, R;Ruiz-Rosado, JD;Partida-Sanchez, S;Guerau-de-Arellano, M;Dhakal, P;Kuivaniemi, H;Hans, CP; (2019) "Pharmacological inhibition of Notch signaling regresses pre-established abdominal aortic aneurysm." Sci Rep
- Hayley I. Muendlein, David Jetton, Wilson M. Connolly, Keith P. Eidell, Zoie Magri, Irina Smirnova, Alexander Poltorak (2020) "cFLIPL protects macrophages from LPS-induced pyroptosos via inhibition of complex II formation." Science
- Ornell, K;Mistretta, K;Newman, E;Ralston, C;Coburn, J; (2019) "Three-Dimensional, Scaffolded Tumor Model to Study Cell-Driven Microenvironment Effects and Therapeutic Responses." ACS Biomater. Sci. Eng.
- Zheng, P;Hu, M;Xie, Y;Yu, Y;Jaaro-Peled, H;Huang, XF; (2019) "Aripiprazole and haloperidol protect neurite lesions via reducing excessive D2R-DISC1 complex formation." Prog. Neuropsychopharmacol. Biol. Psychiatry
- Ling, T;Maier, J;Das, S;Budhraja, A;Bassett, R;Potts, MB;Shelat, A;Rankovic, Z;Opferman, JT;Rivas, F; (2019) "Identification of substituted 5-membered heterocyclic compounds as potential anti-leukemic agents." Eur J Med Chem
- Seo, Y;Lee, J;Park, S;Namkung, W;Kim, I; (2020) "Expansion of chemical space based on a pyrrolo[1,2-a]pyrazine core: Synthesis and its anticancer activity in prostate cancer and breast cancer cells." European Journal of Medicinal Chemistry
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科学期刊
商务期刊
Genetic Engineering & Biotechnology News (1)
科学海报
- Consistent, Repeatable Wound Healing Assays Incorporating a Novel, Automated Scratch Tool and Kinetic Label-Free Imaging (February 6, 2019)
- Advanced 2D Wound Healing Assay Procedures Performed using a Novel, Automated Scratch Tool, High Contrast Brightfield and Fluorescence Kinetic Imaging (February 6, 2019)
- Quantitative Microscopy of Angiogenesis in Zebrafish Embryos (February 6, 2019)
- Automated Analysis of Neutrophil NETosis Activity (February 6, 2019)
- Monitoring Cellular Stress Response and Inhibition of GPCR-Dependent Calcium Signaling Using Expressed Biosensors (December 9, 2018)
- Autophagy Analysis Using Object Spot Counting (February 5, 2018)
- Evaluating Ethanol Induced Cell Death in Zebrafish (February 5, 2018)
- Automated imaging-based technique for monitoring of Ca2+ and DAG biosensors enables detailed characterization of GPCR kinetics (December 4, 2017)
- Characterizing GPCR Activation Using Automated Live Cell Imaging (February 13, 2017)
技术注释
动态摘要
- Viral Plaque Assay (August 19, 2020)
- Analysis of RelA Nuclear Translocation (January 9, 2020)
- Rapid Cytotoxicity Determination in 384-well Microplates with Wide Field of View Camera (September 5, 2019)
- Quantitative Multiplexed Imaging of Mixed Bacteria (May 22, 2019)
- Characterizing Both Rapid and Long-Term Treatment Effects Using Expressed Biosensors and Automated Live-Cell Imaging (May 3, 2019)
- Automated Analysis of Neutrophil Netosis (April 25, 2019)
- Analyzing Tail Fin Regeneration in Zebrafish Embryos (March 12, 2019)
- Analyzing Angiogenesis in Zebrafish Embryos (March 5, 2019)
- Quantifying Morphological Changes in Zebrafish Embryos Exposed to Toxins (January 30, 2019)
- 3D Kinetic NK Cell Cytotoxicity Assay (November 13, 2018)
- Automatic Transfection Efficiency Calculation in Microplates (November 13, 2018)
- Color Brightfield Imaging H&E Stained Tissue (November 13, 2018)
- Comet Assay: Single Cell Genotoxicity Measurement (November 13, 2018)
- Automated Wound Creation for Scratch Wound Healing Assays (November 13, 2018)
- Quantifying Poly-Glutamine Aggregates in C. Elegans Using vivoChip (August 24, 2018)
- Automated Cell Fixing, Staining and Immunofluorescence in Microplates (August 3, 2018)
- Counting Caenorhabditis Elegans in 96-Well Plates (July 31, 2018)
- Label-Free Tumor Invasion Assay Using 3D Tumor Spheroids (June 19, 2018)
- High Resolution Imaging of Cells Undergoing Mitosis in Microplates (April 6, 2018)
- High Throughput Cell Migration Assay (April 5, 2018)
- Direct Fluorescence Assay (DFA) (April 2, 2018)
- Measuring Apoptosis in Zebrafish Treated with Ethanol (March 26, 2018)
- Quantifying Cancer Biomarker Gene Expression Using RNA FISH (March 21, 2018)
- Live Cell Imaging of Apoptosis and Necrosis (March 20, 2018)
- Gram Stain Imaging (March 19, 2018)
- Acid Fast Bacteria (AFB) Scoring (March 19, 2018)
- Kinetic Characterization of Gs- and Gi-Dependent Regulation of cAMP (February 16, 2018)
- γH2AX Foci Spot Counting as a Determination of Genotoxicity (February 16, 2018)
- Phagocytosis Assay (February 16, 2018)
- Imaging and Quantification of T Cell Mediated Cytotoxicity (December 7, 2017)
- Image-Based Tracking and Quantification of T Cell Activation (December 7, 2017)
- Cell Proliferation - Label-free Confluence (November 15, 2017)
- Non-Alcoholic Steatohepatitis (NASH) Imaging Assay (November 6, 2017)
- Mitochondrial Membrane Potential Analysis Using Object Spot Counting (August 4, 2017)
- Sub-Micron Spot Quantitation of Centromeres (July 28, 2017)
- Kinetic Cytotoxicity Using Cell Counting (June 16, 2017)
- Autophagy Analysis Using Object Spot Counting (June 14, 2017)
- Cell Migration Assay: 3D Bioprinting (May 4, 2017)
- Calcium Kinetics (April 28, 2017)
- Fluorescence-based Plaque Assay (February 24, 2017)
网络视频
- Drug Discovery & Development Virtual Conference - On Demand (December 9, 2020)
- Virology and Infectious Disease Virtual Conference - On Demand (October 22, 2020)
- Techniques for Improving Cell Culture Quality Control and Assay Optimization - OnDemand (June 17, 2020)
- 3D Culture Methods and Imaging Considerations - On Demand (April 29, 2020)
- Zebrafish Imaging with Quantitative Analysis - On Demand (March 20, 2019)
- Image Analysis 101 - Case Studies in Microbiology - On Demand (November 7, 2018)
- Quantitative Intracellular and Intranuclear Spot Analysis Using Digital Microscopy (November 29, 2017)
- Enabling Quantitative Cellular Imaging (November 29, 2016)
- Automated Live Cell Imaging (May 26, 2016)