Resources

In-vitro cell-based assays that utilize a 3D structure of aggregated cells using hydrogels, scaffolds or spheroids to provide more physiologically relevant data.

In-vitro assays using either cells or purified enzyme for Lead Optimization of small molecules in drug discovery; drug absorption, drug metabolism and drug cytotoxicity assays

Demonstration of automated procedures for various assays using microplates.

Assays using purified drug target in Hit ID and Hit to Lead small molecule screening efforts.

Assays assisting in R&D efforts to produce biofuels from corn, lignocellulosic material and algae.

Quantification of biological markers (i.e. proteins, DNA, RNA, etc.) associated with disease, toxicity and drug efficacy from biofluids (i.e. serum/plasma).

Microplate assays used for biologic drug discovery and development: clonal selection, characterization, formulation studies and immunogenicity.

Quantitative assays of cellular function using a wide range of microplate reader optical detection modes.

Imaging of cells after fixation or lysis using fluorescence microscopy.

Kinetic studies using purified enzymes in a microplate format.

Cell-based and biochemical assays to measure activity and small molecule modulation of epigenetic target proteins.

Assays measuring contaminants in food and beverages including bacteria and processing by-products that influence customer health and product quality.

The study of the microscopic anatomy of tissues by sectioning and staining, typically with colored dyes such as H&E using an optical microscope.

Kinetic imaging of live cells under environment control using brightfield, high contrast brightfield. phase contrast and fluorescence microscopies.

Quantification of dsDNA, ssDNA, RNA and µRNA using micro-volume, microplate and 1 cm pathlength devices for downstream processes such as PCR, qPCR and sequencing.

Determination of fundamental constants of physical chemistry.

Quantification of total protein using micro-volume, microplate and 1 cm pathlength devices for downstream processes such as PAGE and mass spectrometry.

Assay workflows that monitor and validate stem cell differentiation.

Spectrophotometric measurements of bacteria, yeast and other non-adherent cells based on light scatter, typically at A600.

Assays used in animal husbandry to assess health and disease.