BioTek: Stem Cell Differentiation

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  Cell migration and invasion are live cell kinetic assays useful in oncology research. The principle difference between migration and invasion is that migration refers to normal cell movement; whereas invasion describes cells actively invading surrounding tissue. It can do this under the influence of a chemoattractant gradient and secretion of proteases. There are numerous methods for performing these assays including scratch assays performed on a monolayer of cells adhered to plasticware (microplates or culture inserts) or using 3D cell culture models.
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  Biochemical assays run the gamut from routine ELISAs to micro-volume nucleic acid and protein quantification. Endpoint and kinetic, single- and multi-wavelength assays are essential experimental tools. BioTek’s multi-mode readers have the flexibility to accommodate a very broad range of applications with superior performance.
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  G-protein coupled, seven-transmembrane (7-TM) receptors (GPCRs) represent large, diverse gene families found in fungi, plants and animals. The GPCR family of receptors is involved primarily with internalizing extracellular environmental signals via interaction with intracellular G-proteins. GPCR ligands and modulators range from peptide and non-peptide molecules to chemokines, nucleosides, growth factors and light.
- Stem Cell Research
  Research into the reprogramming of somatic cells into pluripotent stem cells received the Nobel Prize in 2012. The long term importance of this research resides in the use of stem cells for regenerative therapies; for the short term, however these cells represent a potential unlimited source of highly physiologically relevant cells, akin to human primary cells, that can be used as drug discovery reagents.
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  Synergy Neo2 and Synergy H1 Now Available with Expanded Temperature Control Range
  July 28, 2021 - Now with temperature control up to 70 ºC, BioTek’s Synergy Neo2 Hybrid Multi-Mode Reader and Synergy H1 Hybrid Multi-Mode Reader aid in more assay workflows than ever before. Application flexibility extends to enzyme kinetics, protein stability and aggregation, and projects incorporating loop mediated isothermal amplification (LAMP) assays. 浏览更多
  
  BioTek's Cytation 7 Cell Imaging Multi-Mode Reader Named ‘Best New Drug Discovery & Development Product’ at Scientists’ Choice Awards
  May 5, 2021 - BioTek Instruments is pleased to announce that the Cytation 7 Cell Imaging Multi-Mode Reader was awarded ‘Best New Drug Discovery & Development Product’ of 2020. The honor was voted upon by SelectScience members across the world and celebrated at the 2021 Scientists’ Choice Awards online awards ceremony. 浏览更多
  
  BioTek Announces New Cytation C10 Confocal Imaging Reader
  February 2, 2021 - BioTek Instruments, a part of Agilent, is excited to unveil the Cytation C10, an advanced, automated Confocal Imaging Reader. This versatile and multi-functional automated system is ideal for research laboratories and core facilities looking to increase productivity while reaping high-quality qualitative and quantitative data to support cell-based research. 浏览更多
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Stem Cell Differentiation

Research into the reprogramming of somatic cells into pluripotent stem cells received the Nobel Prize in 2012. The long-term importance of this research resides in the use of stem cells for regenerative therapies for the short term., However these cells represent a potential unlimited source of highly physiologically relevant cells, akin to human primary cells, that can be used as drug discovery reagents. The process of differentiating stem cells into the somatic cell of choice is a long process requiring careful culturing. The process typically utilizes immunofluorescence techniques to determine progenitor cells and terminally differentiated somatic cells. The Agilent BioTek imaging products with liquid handling and Agilent BioTek BioSpa 8 automated CO₂ incubator have been designed to enable automated stem cell differentiation.

Application Notes:

Related Webinars:

Combining Automated Liquid Handling, Cellular Microscopy and Magnetic Bioprinting to Create Walk Away 3D Oncology, Stem Cell Differentiation, and Toxicity Procedures - On Demand

Related Products:

Agilent BioTek BioSpa Live Cell Imaging System
Agilent BioTek Cytation 7 Cell Imaging Multi-Mode Reader
Agilent BioTek Cytation 5 Cell Imaging Multi-Mode Reader
Agilent BioTek Cytation 1 Cell Imaging Multi-Mode Reader

Learn more about Stem Cell Research applications - search our application notes and technical documentation in resources.

For Research Use Only. Not for use in diagnostic procedures.

RA44256.555162037